Health Benefits and Side Effects of Turmeric vs Curcumin

tumericDeane Alban, Contributor
Waking Times

Turmeric and curcumin have many health benefits but pay attention to their differences and side effects. Learn if they work better as food or supplements …

Historically spices were treasured for the unique flavors they brought to food and for their healing properties.

Most spices provide some medicinal benefits.

But one spice that stands above the rest is turmeric.

The health benefits of turmeric are regularly in the news. It’s been reported as a potential treatment for diseases as diverse as arthritis, cancer, diabetes, heart disease, psoriasis, and Alzheimer’s.

But does this spice live up to its press?

And can you get the benefits you want just from the food you eat? Or do you need to take a turmeric supplement?

What are the differences between turmeric and curcumin?

Are there any side effects or drug interactions to watch out for?

Here’s what we found out.

It Starts with Turmeric

You may have heard the words curry powder, turmeric and curcumin used interchangeably.

They are related but they aren’t the same thing.

  • Turmeric is a spice that comes from the root of Curcuma longa, a beautiful flowering tropical plant native to India.

    Cooking residue found on pottery shards shows that people in parts of Asia cooked with turmeric 4,500 years ago. (1)

    Turmeric is one of several spices used to make curry powder, an essential ingredient in south Asian cuisine.

    It’s usually used dry but the root can also be grated fresh like ginger.

    Turmeric has hundreds of known components but it’s mainly curcumin that gives this spice its distinctive golden hue.

    Curcumin is the active ingredient that makes this spice “gold” for your health as well.

    Traditional Turmeric Health Benefits

    Turmeric has been used for healing for thousands of years going back to Ayurveda, India’s 5,000-year-old natural healing system. (2)

    This versatile spice was used internally to improve digestion, dissolve gallstones, relieve arthritis, and alleviate symptoms of allergies and colds.

    It was applied externally for wounds and skin conditions. (3)

    It was also used as a beauty treatment.

    Soaps and creams containing turmeric are experiencing a surge in popularity today.

    Turmeric paste is still applied to the skin of  both the bride and groom in a ceremony before marriage in some parts of India, Bangladesh, and Pakistan to beautify skin and as a form of good luck.

    The Curcumin Quandary

    Unlike turmeric, which has been used for healing for thousands of years, curcumin was identified only about 100 years ago. (4)

    Curcumin is extracted from turmeric for its strong antioxidant and anti-inflammatory properties. (5)

    But if you’re looking for optimal medicinal value from curcumin, there’s a quandary.

    Curcumin  makes up only about 3% of most turmeric powders. And curry powders generally contain very little of the stuff. (67)

    Curcumin either in turmeric or on its own is not very well absorbed.

    In fact, studies show that 40-85% of curcumin supplements pass through the intestines unchanged. (8)

    Scientists are working on high-tech ways to make curcumin more bioavailable like using nanoparticles or combining it with phosphatidylserine. (910)

    But it turns out that ancient cuisines worked out the answer to getting full turmeric benefits thousands of years ago.

    By adding black pepper to curry powder mix, it greatly increases the bioavailability of curcumin.

    It’s now known that the compound piperine found in black pepper increases curcumin absorption by a whopping 2000%. (11)

    The bioavailability of curcumin is also increased when cooked in oil. (12) Again, tradition has this covered.

    Indian cuisine liberally uses peanut, sesame and coconut oil, and butter-based ghee. (13)

    Boiling turmeric in water, as is done to make turmeric tea, also increases bioavailability. (14)

    Proven Health Benefits of Curcumin and Turmeric

    Turmeric contains hundreds of compounds, each with its own unique properties.

    So far, turmeric has been found to contain at least 20 compounds that are antibiotic, 14 known cancer preventatives, 12 that are anti-tumor, 12 anti-inflammatory, and at least 10 antioxidants. (15)

    But of all the compounds in turmeric, curcumin is by far the most promising and is definitely the most widely studied. (16)

    Curcumin benefits are derived from its natural anti-inflammatory, antioxidant, antiviral, antibacterial, antifungal, and anti-cancer properties. (17)

    A quick look on Google Scholar gives over 160,000 results for scientific studies done on turmeric and curcumin health benefits.

    More research has been done on curcumin since it’s an isolated compound with effects that are more drug-like than a kitchen spice.

    Here’s a list of conditions that turmeric and curcumin have been found to help along with examples of promising scientific findings.

    Allergies and Asthma 

    Allergies and asthma have been on the rise, particularly in industrialized countries.

    Curcumin can help alleviate the symptoms of allergies by inhibiting histamine release from mast cells. (18)

    It reduces both the inflammation and bronchospasms experienced by asthma sufferers. (19)

    Alzheimer’s Disease

    One of the most exciting turmeric benefits is that it may prevent Alzheimer’s.

    Elderly villagers in India who eat turmeric as a regular part of their cuisine have the lowest rate of Alzheimer’s in the world. (20)

    This isn’t a coincidence.

    Curcumin reduces the brain inflammation and breaks up brain plaques associated with Alzheimer’s. (21)


    Curcumin’s natural anti-inflammatory properties rival those of nonsteroidal anti-inflammatory drugs (NSAIDs).

    When tested against drugs used to extinguish the pain and inflammation of arthritis, curcumin held its own.

    It performs as well as or even better than over-the-counter and prescription NSAIDs. (22)

    Curcumin is more effective than anti-inflammatory drugs for rheumatoid arthritis. (23)

    Bacterial Infections and Viruses

    Test tube and animal studies suggest turmeric kills bacteria and viruses but so far this has not been proven in people. (24)

    The National Center for Biodefense and Infectious Diseases is currently studying the effects of curcumin on Rift Valley fever. They plan to extend their research to other viruses including HIV. (2526)

    Brain Boosting

    Curcumin is a potent antioxidant that readily crosses the blood-brain barrier. (27)

    It can improve memory and concentration by increasing blood flow and neurotransmitter formation. (2829)

    There’s evidence that curcumin can boost levels of serotonin and dopamine. (30)

    Curcumin increases levels of brain-derived neurotrophic factor (BDNF), a protein that stimulates brain cell production. (31)

    Another compound in turmeric —  turmerone — stimulates the production of new neurons. This makes it a potential candidate for treating neurological disorders, such as stroke and Alzheimer’s. (32)


    Curcumin shows protective effects against many cancers including gastrointestinal, genitourinary, gynecological, hematological, pulmonary, thymic, brain, breast, and bone. (33)

    Curcumin significantly inhibits growth of human breast cancer. (34)

    Curcumin has been found to kill cancer cells by several diverse mechanisms.

    Its ability to selectively kill tumor cells while not harming normal cells makes curcumin an attractive candidate as a cancer treatment. (35)

    Curcumin works synergistically with both chemotherapy and radiation treatments, increasing their effectiveness. (36)

    Dr. Saraswati Sukumar is a cancer researcher at Johns Hopkins who has been involved in over 300 studies on the disease. (37)

    In a recent interview, she revealed that she’s found food provides more turmeric benefits than supplements. (38) Turmeric in capsules is very insoluble rendering them less effective.


    Three groups of patients with depression were given either curcumin or Prozac, or a combination of both. Somewhat surprisingly, curcumin supplements were as effective as Prozac. Patients who took both curcumin and Prozac fared best. (39)

    Curcumin can help even major depressive disorder. (40)

    If you have depression, turmeric or curcumin supplements can be taken indefinitely.

    They can safely be combined with antidepressant drugs or with other natural depression remedies such as St. John’s wort and SAMe. (41)

    Diabetes and Pre-Diabetes

    Curcumin holds promise for preventing and controlling diabetes.

    One study followed 240 pre-diabetic adults over 9 months. During that time, 19 of the placebo patients developed full-blown type 2 diabetes while none of the curcumin-taking patients did. (42)

    Curcumin can mitigate diabetic complications including neuropathy. And since it tends to lower blood sugar levels, it shows promise as a drug-free way to control blood sugar levels. (43)

    Digestive Problems

    Using curcumin for digestive problems shows mixed results. While it can help ulcerative colitis, it can aggravate conditions like GERD and ulcers. (44)

    Fatigue and CFS

    Fatigue is such a common problem, you might even think it’s normal to need coffee to get through the day.

    Fatigue can be caused by your lifestyle or it can be a symptom of an underlying condition like fibromyalgia or chronic fatigue syndrome.

    Taking curcumin supplements can dramatically decrease fatigue, particularly among the elderly. (45)

    The use of curcumin after surgery reduces post-operative pain and fatigue. (46)

    Curcumin significantly reduces oxidative stress and fatigue in chronic fatigue syndrome, making it a potential treatment for CFS. (4748)

    Heart Disease

    The antioxidant and anti-inflammatory effects of curcuminoids protects against atherosclerosis. (49)

    Curcumin reduces post-bypass heart attack risk by 56%. (50)

    Obsessive-Compulsive Disorder (OCD)

    Curcumin has been found to help alleviate obsessive actions and improve associated memory loss by increasing levels of the neurotransmitters dopamine and serotonin. (51)

    Parkinson’s Disease

    Curcumin shows promise for treating Parkinson’s by preventing clumping of a protein found in the first stages of this disease. (5253)

    It is currently being studied as a Parkinson’s treatment by the Michael J. Fox Foundation. (5455)


    Psoriasis is a chronic, inflammatory skin condition.

    The usual medical treatment is the application of topical corticosteroids and sometimes phototherapy.

    Curcumin capsules were found to be a safe and effective adjunct to topical treatment. Twelve weeks of curcumin improved inflammatory markers by 48%.

    Results were so encouraging that researchers concluded that curcumin will be used more for treating psoriasis in the future. (5657)

    Wound Healing

    Curcumin can speed up the healing of wounds. (58)

    Curcumin in combination with ginger promotes wound healing when used either orally or topically. (59)

    Turmeric and Curcumin Side Effects

    Turmeric and curcumin are beginning to sound like miracle cures.

    And since they are natural they must be safe, right?

    Turmeric consumed as a spice in food is considered safe.

    There are almost no known turmeric side effects except for an increased risk of kidney stones in those susceptible. (60)

    But we were surprised to learn that turmeric and curcumin supplements carry a large number of possible side effects, interactions, and warnings.

    While clearly turmeric and curcumin are not identical, their respective side effects and reactions are treated as one on sites like,, and the National Institutes of Health’s MedLine.

    All three sites were in agreement that you should not take turmeric or curcumin supplements if:

    • You are pregnant. Curcumin stimulates the uterus and raises the risk of a miscarriage. The safety of this spice while breast feeding has not been established.
    • You are trying to conceive. If you are having trouble conceiving, turmeric could add to your difficulties.
    • You have a hormone-sensitive condition. Turmeric can act like estrogen so should be avoided if you have reproductive cancer, endometriosis, or uterine fibroids.
    • You have gallstones or gallbladder disease. Turmeric can make gallbladder problems worse.
    • You are scheduled for surgery in the next two weeks. Turmeric increases the risk of bleeding.
    • You take medications that slow clotting such as aspirin, clopidogrel, diclofenac, ibuprofen, naproxen, and warfarin. This mix increases the risk of bruising and bleeding.
    • You have GERD, ulcers, or other stomach problems. Turmeric can make GERD worse and cause gastric irritation, stomach upset, nausea, and diarrhea.
    • You take drugs to reduce stomach acid. Turmeric can interfere with the actions of medications like Zantac, Tagamet, and Nexium, increasing the production of stomach acid. (61)
    • You take diabetes medication. Turmeric increases the risk of hypoglycemia (low blood sugar).
    • You have an iron deficiency. Turmeric can prevent the absorption of iron.

    Some supplements contain piperine to enhance curcumin bioavailability. However piperine can also increase the bioavailability and slow the elimination of a number of drugs, including phenytoin, propranolol, and theophylline. (62)

    Seventy drugs are known to interact adversely with curcumin and turmeric supplements. Find a complete list of turmeric interactions here.

    Turmeric Dosage

    According to the University of Maryland’s Complementary and Alternative Medicine Guide, here are suggested turmeric dosages for adults:

    • Cut root: 1.5-3 grams per day
    • Dried, powdered root: 1-3 grams per day
    • Fluid extract (1:1): 30-90 drops per day
    • Tincture (1:2): 15-30 drops, 4 times per day

    Their recommended curcumin dosage for a standardized powder supplement is 400-600 mg, 3 times per day.

    Look for products standardized for 95% curcuminoids that also contain piperine or black pepper extract. Follow the dosage instructions on labels. (63)

    Turmeric Tea

    The people of Okinawa, Japan are the longest-lived in the world, with an average life span of 81.2 years.

    And they drink large amounts of turmeric tea. (64)

    Turmeric tea is a great compromise between to trying to get enough turmeric into your daily diet and taking supplements.

    Boiling turmeric in water for 10 minutes increases the solubility of curcumin 12 times! (65)

    To make basic turmeric tea, put 1/2 teaspoon of turmeric powder in 1 cup of water and simmer for 10 minutes. Strain if needed and serve.

    If you actually enjoy it, you’re in luck.

    Most people aren’t too crazy about it. It’s very bitter and medicinal-tasting.

    I’ve been experimenting to find a recipe that’s both healthy and delicious.

    This recipe is tasty and assures maximum bioavailability due to the addition of coconut oil — one of our favorite healthy fats.

    Liquid Gold Turmeric Tea 

    • 1/2 cup water
    • 1/2 teaspoon turmeric powder
    • 1/2 cup coconut milk
    • 1 tablespoon coconut oil
    • Honey or stevia to taste

    Bring water to a boil. Add turmeric powder and simmer gently for 10 minutes.
    Add coconut milk and coconut oil. Heat until warmed through.
    Sweeten with honey or stevia to taste.

    Feel free to experiment with the ingredients and proportions to create the brew that is just right for you.

    You can substitute almond milk or regular milk for coconut milk.

    Ghee — traditional clarified Indian butter — works great instead of coconut oil and adds a rich buttery flavor.

    A good friend suggested adding a little rum to make a Hot Turmeric Toddy!

    Turmeric vs Curcumin in a Nutshell

    You’ve heard all the pros and cons of turmeric health benefits found in food versus curcumin supplements.

    If you’re a little confused, I felt the same way when I started writing this article.

    Here’s our take plus a few words from the experts …

    Turmeric as a spice has a long history of safe and effective use.

    It’s known that when turmeric is cooked with oil, boiled, or combined with black pepper, its bioavailability is greatly increased.

    While there are turmeric capsules and turmeric tinctures available, their bioavailability is questionable and are more likely to cause side effects.

    Curcumin is an isolated compound with a relatively short history.

    Most studies on curcumin end with a statement like this:

    “Results look promising. More research needed.”

    It’s not always safe, especially if you are already taking any medications or have an existing health condition.

    If you decide to take a curcumin supplement look for a standardized extract that has taken measures to enhance bioavailability like the addition of piperine, phosphatidylserine, or the use of nano-particles.

    Otherwise your supplement may be passing straight through you.

    Dr. Andrew Weil, founder of the Arizona Center for Integrative Medicine, sums up our feelings about turmeric vs curcumin:

    “…until proven otherwise in head to head studies, whole plants are usually a better choice than isolates. On the other hand, curcumin appears to have a more rapid and dramatic effect, and may be the better choice as a therapeutic (rather than a preventative) preparation.”

    Cancer expert Dr. Saraswati Sukumar believes the liberal use of turmeric in cooking is all you need to get therapeutic amounts.

    We agree that it’s prudent to start first with turmeric in food and tea for that sweet spot of maximum benefits with virtually no risk of side effects.

    And if you don’t get the results you want, you can try turmeric supplements.

    If that still doesn’t bring the relief you’re looking for, then you can try curcumin supplements, staying mindful of interactions and side effects.

    About the Author

    Deane Alban holds a bachelor’s degree in biology and has taught and written on a wide variety of natural health topics for over 20 years. Her current focus is helping people overcome brain fog, “senior moments”, and other signs of mental decline now, and preventing Alzheimer’s and dementia in the future.

    The human brain is designed to last a lifetime, but modern life takes a greater toll on the brain than most people realize. Deane teaches the best ways to keep your brain healthy and stay mentally sharp for life at her website where you can learn how to make your brain sharp again.

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